Biologia Celular e Molecular

Théo de Araújo Santos

 

Possui graduação em Ciências Biológicas pela UFBA (2006), mestrado e Doutorado em Patologia Experimental pela UFBA-FIOCRUZ-BA. Desenvolveu parte do seu doutorado na University of Iowa (2011) no Laboratory of Leishmania (Bolsista CNPq-SWE). Realizou Pós-doutorado na área de Imunofarmacologia. Desenvolve pesquisa na área de imunologia, biologia celular e parasitologia com ênfase na resposta inflamatória na leishmaniose visceral, atuando nos seguintes temas: interação vetor, parasita, célula hospedeira e a participação de corpúsculos e mediadores lipídicos neste contexto. Atualmente é Professor da Universidade Federal do Oeste da Bahia na disciplina de Biologia Celular e Molecular.

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Para mais informações acesse o links abaixo:

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http://lattes.cnpq.br/0781345225284605

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Publicações:

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Rodriguez , N. E. et al. Lipid bodies accumulation in Leishmania infantum-infected C57BL/6 macrophages. PARASITE IMMUNOLOGY, v. 39, p. 42/e12443.-49, 2017. 

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Araújo-Santos, T. et al. . Anti-parasite therapy drives changes in human visceral leishmaniasis-associated inflammatory balance. Scientific Reports, v. 7, p. 4334, 2017. 

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Carvalho, M. O. S. ; Araújo-Santos, T. et al. Inflammatory mediators in sickle cell anaemia highlight the difference between steady- state and crisis in paediatric patients. BRITISH JOURNAL OF HAEMATOLOGY, p. BJH14896, 2017.

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Tavares, N. et al. Degranulating Neutrophils Promote Leukotriene B4 Production by Infected Macrophages To Kill Leishmania amazonensis Parasites. J. Immunol. (2016). doi:10.4049/jimmunol.1502224

 

Vita, W., Santana, F. De & Galvão, B. M. Comparison of the biocompatibility of grey mineral trioxide aggregate and sealapex plus zinc oxide in rat subcutaneous tissue. 21, 136–144 (2015).

 

Oliveira-Filho, J. et al. COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease. J. Stroke Cerebrovasc. Dis. 24, 1817–1822 (2015).

 

Araújo-Santos, T. et al. Prostaglandin E2/Leukotriene B4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection. Parasit. Vectors 7, 1–8 (2014).

 

Araujo-Santos, T. et al. Role of Prostaglandin F2 Production in Lipid Bodies From Leishmania infantum chagasi: Insights on Virulence. J. Infect. Dis. 210, 1951–1961 (2014).

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Tavares, N. M. et al. Understanding the Mechanisms Controlling Leishmania amazonensis Infection In Vitro: The Role of LTB4 Derived From Human Neutrophils. J. Infect. Dis. 210, 656–666 (2014).

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Luz, N. F. et al. Heme Oxygenase-1 Promotes the Persistence of Leishmania chagasi Infection. J. Immunol. 188, 4460–7 (2012).

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Prates, D. B. et al. New Insights on the Inflammatory Role of Lutzomyia longipalpis Saliva in Leishmaniasis. J. Parasitol. Res. 2012, 643029 (2012).

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Prates, D. B. et al. Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils. J. Leukoc. Biol. 90, 575–82 (2011).

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Araújo-Santos, T. et al. Lutzomyia longipalpis saliva triggers lipid body formation and prostaglandin E₂ production in murine macrophages. PLoS Negl. Trop. Dis. 4, e873 (2010).

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Andrade, B. B. et al. Heme impairs prostaglandin E2 and TGF-beta production by human mononuclear cells via Cu/Zn superoxide dismutase: insight into the pathogenesis of severe malaria. J. Immunol. 185, 1196–204 (2010).

 

Silva, T. R. M. Da et al. Control of Mycobacterium fortuitum and Mycobacterium intracellulare infections with respect to distinct granuloma formations in livers of BALB/c mice. Mem. Inst. Oswaldo Cruz 105, 642–648 (2010).